hrp0089p2-p155 | Fat, Metabolism and Obesity P2 | ESPE2018

Associations between Body Fat Mass and Internalizing and Externalizing Behaviors and Anxiety in Children and Adolescents

Christaki Eirini , Bastaki Despoina , Valavani Eleni , Kanaka-Gantenbein Christina , Bosciero Dario , Chrousos George , Pervanidou Panagiota

Introduction: Body composition analysis is a painless, bloodless and highly informative method of assessing health indicators that can be used extensively in the pediatric population. This is particularly important granted that the prevalence of childhood obesity has been increasing at a fast pace worldwide. Increased adiposity in children and adolescents is an important issue for children’s growth and psychologic development. Assessing the psychosocial status of children...

hrp0089p2-p179 | Fat, Metabolism and Obesity P2 | ESPE2018

Body Composition Parameters, Systemic Inflammation and Metabolic Syndrome Manifestations in Children and Adolescents

Christaki Eirini , Pervanidou Panagiota , Bastaki Despoina , Valavani Eleni , Kanaka-Gantenbein Christina , Boschiero Dario , George Chrousos

Introduction: Increased adiposity has been associated with smoldering systemic inflammation and metabolic syndrome manifestations, leading to further morbidity by increasing the risk for type 2 diabetes mellitus and cardiovascular disease in adults. Similar analyses have not been performed systematically in children and adolescents.Hypothesis: This study investigates the interrelations between body composition parameters and indices of inflammation and m...

hrp0086p1-p21 | Adrenal P1 | ESPE2016

Increased Salivary and Hair Cortisol and Decreased Salivary Alpha-Amylase Concentrations in Obese Prepubertal Girls

Papafotiou Chrysanthe , Christaki Eirini , van den Akker Erica , Wester Vincent , Apostolakou Filia , Papassotiriou Ioannis , Chrousos George , Pervanidou Panagiota

Background: Obesity has been associated with perturbations of the hypothalamic–pituitary–adrenal (HPA) axis and the sympathetic nervous system (SNS). Scalp hair cortisol has been recognized as a reliable index of long-term cortisol concentrations.Objective and hypotheses: Aim of this study was to compare indices of HPA axis and SNS activities, such as, respectively, the salivary cortisol and alpha-amylase diurnal patterns, and their relations i...

hrp0086p1-p478 | Fat Metabolism and Obesity P1 | ESPE2016

BMI Correlates Positively with Hair Cortisol, whereas Excessive Body Fat Correlates Positively with Hair Cortisol: Salivary Cortisol and Fasting Insulin Concentrations in Prepubertal Girls

Christaki Eirini , Papafotiou Chrysanthe , Bastaki Despoina , van den Akker Erica L.T. , Wester Vincent L. , Boschiero Dario , Pervanidou Panagiota , Kanaka-Gantenbein Christina , Chrousos George

Background: Chronic stress and increased adiposity have been associated with each other in children. Further studies are needed, however, to evaluate both the directionality of this association and the mediating metabolic mechanisms.Objective and hypotheses: This study investigates the interrelations between BMI, body composition parameters, indices of the stress response, such as hair and salivary cortisol levels, and, metabolic mediators, such as insul...